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- Title
Surgical Outcomes in Patients With Centrally Located Non-small Cell Lung Cancer.
- Authors
TAKUMA TSUKIOKA; NOBUHIRO IZUMI; HIROAKI KOMATSU; HIDETOSHI INOUE; YUMI MATSUDA; RYUICHI ITO; TAKUYA KIMURA; NORITOSHI NISHIYAMA
- Abstract
Background/Aim: Identification of prognostic factors is helpful in selecting optimal treatment for centrallylocated non-small cell lung cancer (NSCLC). This study aimed to detect prognostic factors in patients with centrallylocated NSCLC. Patients and Methods: NSCLCs in the hilar area requiring pneumonectomy or sleeve lobectomy for complete removal are defined as centrally-located NSCLCs. We retrospectively investigated the clinical courses of 45 patients with such lesions. Results: Sleeve lobectomies were performed on 33 patients and pneumonectomies on 12. Three and five-year survival rates were 72% and 62%, respectively. Presence of comorbidities (p=0.013), severe symptoms (p=0.001), high white cell count (p=0.001), and pathological T3-4 stage (p=0.004) were identified as independent predictors of poor prognosis. Operative procedures did not correlate with outcomes (p=0.722). Conclusion: Presence of comorbidities, severe symptoms, high white cell counts, and pathological T stage are independent predictors of poor prognosis. These data can contribute in selecting appropriate treatments for such lesions.
- Subjects
NON-small-cell lung carcinoma; PNEUMONECTOMY; LOBECTOMY (Lung surgery); PROGNOSIS; COMORBIDITY
- Publication
In Vivo, 2021, Vol 35, Issue 5, p2815
- ISSN
0258-851X
- Publication type
Article
- DOI
10.21873/invivo.12568