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- Title
Effects of Phentolamine on Responses to PAMP in the Hindquarters Vascular Bed of the Rat.
- Authors
Noosaman, Bobby D.; Kaye, Alan D.; Champion, Hunter C.; Bin Kang; Feng, Chang J.; Kadowitz, Philip J.
- Abstract
The article discusses a study which investigated the effects of phentolamine on proadrenomedullin NH2-terminal 20 peptide (PAMP) responses in the systemic and hindquarters vascular bed of the rat. Intravenous and intra-arterial injections of PAMP were administered to test for the effects of the phentolamine which is an alpha receptor blocking agent. The result of the study indicated that PAMP has systemic vasodepressor and vasodilator activity in the hindquarters vascular bed of the rat independent of phentolamine.
- Subjects
PHENTOLAMINE; LABORATORY rats; VASODILATORS; PEPTIDES; ALBUTEROL
- Publication
Journal of Cardiovascular Pharmacology & Therapeutics, 1997, Vol 2, Issue 3, p153
- ISSN
1074-2484
- Publication type
Article
- DOI
10.1177/107424849700200302