We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Packaging systems for generating SARS-CoV-2 pseudoviruses: A mini review.
- Authors
Chin Wong, Jacqueline Tze; Teoh, Peik Lin
- Abstract
The COVID-19 pandemic has caused a huge damage to global society, not only affecting health aspect but also economics. The development of effective vaccines and therapeutics has been a critical step in the fight against this pandemic, and much research has been committed to studying the causative virus, SARS-CoV-2. Pseudovirus, a valuable research tool that allows investigating SARS-CoV-2 in a safe and controlled environment, has gained significant attention in recent years. It is a promising tool for examining the behaviour of the viral envelope protein and the development of vaccines and therapeutics. Finding an optimized pseudovirus system is crucial for various scientific and medical research applications, especially in the study of viral infections, immune responses and vaccine development. It plays a crucial role in advancing our understanding of viral diseases to combat with the new variants. This minreview focuses on the concept of pseudovirus systems and factors affecting the pseudovirus yield.
- Subjects
VIRAL envelope proteins; LENTIVIRUSES; DRUG development; COVID-19 pandemic; ANTIVIRAL agents
- Publication
Malaysian Journal of Microbiology, 2023, Vol 19, Issue 6, p837
- ISSN
1823-8262
- Publication type
Article
- DOI
10.21161/mjm.230026