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- Title
AVALIAÇÃO DO USO DE PROCALCITONINA COMO AUXILIAR NO MANEJO DO TRATAMENTO ANTIMICROBIANO DE PACIENTES CRÍTICOS.
- Authors
HAVREXAKI, JULIANA; SCHAIA ROCHA, AMANDA; BAGLIE, SINVALDO; MIYOSHI, EDMAR
- Abstract
The rational use of antimicrobials promotes lower risk for the patient and the development of bacterial resistance. Thus, the objective was to evaluate the use of procalcitonin (PCT) as an auxiliary test in monitoring antimicrobial treatment for patients with respiratory infection (RI) or sepsis, admitted to Intensive Care Units (ICU). The data were collected from electronic medical records. The 235 selected patients were divided based on adherence to the institutional protocol that guides the request for PCT, into group 1 (PCT in accordance with the protocol) (n=33); group 2 (PCT not in accordance with the protocol) (n=25) and group 3 (PCT not requested) (n=177). Patients in group 1 had a shorter average duration of antibiotic therapy than the other groups. The length of hospitalization and ICU stay was shorter in group 3 compared to group 2. There was a statistical difference in outcomes; there was a higher frequency of deaths than discharges in groups 2 and 3, unlike group 1, where discharges outnumbered deaths. Discontinuation of treatment based on a PCT protocol leads to a reduction in antimicrobial exposure in patients with lower respiratory tract infections or sepsis, with no negative impact on mortality.
- Publication
Brazilian Journal of Surgery & Clinical Research, 2023, Vol 45, Issue 1, p26
- ISSN
2317-4404
- Publication type
Article