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- Title
Genotyping of Hepatitis E Virus from Vietnam.
- Authors
Hijikata, Minako; Hayashi, Shigeki; Trinh, Ngoc Thi; Ha, Le Dang; Ohara, Hiroshi; Shimizu, Yohko K.; Keicho, Naoto; Yoshikura, Hiroshi
- Abstract
To identify the genotype of Vietnamese isolates of human hepatitis E virus (HEV), phylogenetic analysis was performed for the open reading frame (ORF) 1 and ORF2 nucleotide sequences of the viral genome. HEV was detected by RT-PCR in 9 out of 141 sera collected from patients with a diagnosis of acute sporadic hepatitis in Hanoi, Vietnam. All of them had sequences related most closely to genotype 4. In addition, the Vietnamese isolate had a single nucleotide insertion in the ORF 3 region, a characteristic reported for genotype 4 with the possible change of initiation of ORF 3 and ORF 2. Copyright © 2002 S. Karger AG, Basel
- Publication
Intervirology, 2002, Vol 45, Issue 2, p101
- ISSN
0300-5526
- Publication type
Article
- DOI
10.1159/000063231