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Sodium current inhibition following stimulation of exchange protein directly activated by cyclic-3′,5′-adenosine monophosphate (Epac) in murine skeletal muscle.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-36386-0
By:
- Matthews, Hugh R.;
- Tan, Sapphire R. X.;
- Shoesmith, Jonathan A.;
- Ahmad, Shiraz;
- Valli, Haseeb;
- Jeevaratnam, Kamalan;
- Huang, Christopher L.-H.
Publication type:
Article
Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor γ co-activator deficient hearts modelling mitochondrial dysfunction.
Published in:
Bioscience Reports, 2019, v. 39, n. 12, p. 1, doi. 10.1042/BSR20190403
By:
- Edling, Charlotte E.;
- Fazmin, Ibrahim T.;
- Saadeh, Khalil;
- Chadda, Karan R.;
- Ahmad, Shiraz;
- Valli, Haseeb;
- Huang, Christopher L.-H.;
- Jeevaratnam, Kamalan
Publication type:
Article
Ageing in Pgc-1β−/− mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology.
Published in:
Bioscience Reports, 2019, v. 39, n. 4, p. 1, doi. 10.1042/BSR20190127
By:
- Edling, Charlotte E.;
- Fazmin, Ibrahim T.;
- Chadda, Karan R.;
- Ahmad, Shiraz;
- Valli, Haseeb;
- Grace, Andrew A.;
- Huang, Christopher L.-H.;
- Jeevaratnam, Kamalan
Publication type:
Article
Effects of ageing on pro-arrhythmic ventricular phenotypes in incrementally paced murine Pgc-1β hearts.
Published in:
Pflügers Archiv: European Journal of Physiology, 2017, v. 469, n. 12, p. 1579, doi. 10.1007/s00424-017-2054-3
By:
- Ahmad, Shiraz;
- Valli, Haseeb;
- Edling, Charlotte;
- Grace, Andrew;
- Jeevaratnam, Kamalan;
- Huang, Christopher
Publication type:
Article
The RyR2-P2328S mutation downregulates Na1.5 producing arrhythmic substrate in murine ventricles.
Published in:
Pflügers Archiv: European Journal of Physiology, 2016, v. 468, n. 4, p. 655, doi. 10.1007/s00424-015-1750-0
By:
- Ning, Feifei;
- Luo, Ling;
- Ahmad, Shiraz;
- Valli, Haseeb;
- Jeevaratnam, Kamalan;
- Wang, Tingzhong;
- Guzadhur, Laila;
- Yang, Dandan;
- Fraser, James;
- Huang, Christopher;
- Ma, Aiqun;
- Salvage, Samantha
Publication type:
Article
Epac‐induced ryanodine receptor type 2 activation inhibits sodium currents in atrial and ventricular murine cardiomyocytes.
Published in:
Clinical & Experimental Pharmacology & Physiology, 2018, v. 45, n. 3, p. 278, doi. 10.1111/1440-1681.12870
By:
- Valli, Haseeb;
- Ahmad, Shiraz;
- Sriharan, Sujan;
- Dean, Lydia D.;
- Grace, Andrew A.;
- Jeevaratnam, Kamalan;
- Matthews, Hugh R.;
- Huang, Christopher L‐H
Publication type:
Article
Age‐dependent electrocardiographic changes in Pgc‐1β deficient murine hearts.
Published in:
Clinical & Experimental Pharmacology & Physiology, 2018, v. 45, n. 2, p. 174, doi. 10.1111/1440-1681.12863
By:
- Ahmad, Shiraz;
- Valli, Haseeb;
- Salvage, Samantha C.;
- Grace, Andrew A.;
- Jeevaratnam, Kamalan;
- Huang, Christopher L‐H
Publication type:
Article
Ion channels, long QT syndrome and arrhythmogenesis in ageing.
Published in:
Clinical & Experimental Pharmacology & Physiology, 2017, v. 44, p. 38, doi. 10.1111/1440-1681.12721
By:
- Jeevaratnam, Kamalan;
- Chadda, Karan R;
- Salvage, Samantha C;
- Valli, Haseeb;
- Ahmad, Shiraz;
- Grace, Andrew A;
- Huang, Christopher L‐H
Publication type:
Article
Reduced cardiomyocyte Na+ current in the age‐dependent murine Pgc‐1β−/− model of ventricular arrhythmia.
Published in:
Journal of Cellular Physiology, 2019, v. 234, n. 4, p. 3921, doi. 10.1002/jcp.27183
By:
- Ahmad, Shiraz;
- Valli, Haseeb;
- Smyth, Robert;
- Jiang, Anita Y.;
- Jeevaratnam, Kamalan;
- Matthews, Hugh R.;
- Huang, Christopher L.‐H.
Publication type:
Article
Standalone balloon aortic valvuloplasty: Indications and outcomes from the UK in the transcatheter valve era.
Published in:
Catheterization & Cardiovascular Interventions, 2013, v. 81, n. 2, p. 366, doi. 10.1002/ccd.24534
By:
- Khawaja, Muhammed Z.;
- Sohal, Manav;
- Valli, Haseeb;
- Dworakowski, Rafal;
- Pettit, Stephen J.;
- Roy, David;
- Newton, James;
- Schneider, Heiko;
- Manoharan, Ganesh;
- Doshi, Sagar;
- Muir, Douglas;
- Roberts, David;
- Nolan, James;
- Gunning, Mark;
- Densem, Cameron;
- Spence, Mark S.;
- Chowdhary, Saqib;
- Mahadevan, Vaikom S.;
- Brecker, Stephen J.;
- MacCarthy, Philip
Publication type:
Article
Pro-arrhythmic atrial phenotypes in incrementally paced murine Pgc1β−/− hearts: effects of age.
Published in:
Experimental Physiology, 2017, v. 102, n. 12, p. 1619, doi. 10.1113/EP086589
By:
- Valli, Haseeb;
- Ahmad, Shiraz;
- Fraser, James A.;
- Jeevaratnam, Kamalan;
- Huang, Christopher L.‐H.
Publication type:
Article
Atrial Transcriptional Profiles of Molecular Targets Mediating Electrophysiological Function in Aging and Pgc-1 β Deficient Murine Hearts.
Published in:
Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2019.00497
By:
- Edling, Charlotte E.;
- Fazmin, Ibrahim T.;
- Chadda, Karan R.;
- Ahmad, Shiraz;
- Valli, Haseeb;
- Huang, Christopher L.-H.;
- Jeevaratnam, Kamalan
Publication type:
Article
Inhibiting Src family tyrosine kinase activity blocks glutamate signalling to ERK1/2 and Akt/PKB but not JNK in cultured striatal neurones.
Published in:
Journal of Neurochemistry, 2004, v. 88, n. 5, p. 1127, doi. 10.1046/j.1471-4159.2004.02257.x
By:
- Crossthwaite, Andrew J.;
- Valli, Haseeb;
- Williams, Robert J.
Publication type:
Article
Gene and Protein Expression Profile of Selected Molecular Targets Mediating Electrophysiological Function in Pgc-1α Deficient Murine Atria.
Published in:
International Journal of Molecular Sciences, 2018, v. 19, n. 11, p. 3450, doi. 10.3390/ijms19113450
By:
- Chadda, Karan R.;
- Edling, Charlotte E.;
- Valli, Haseeb;
- Ahmad, Shiraz;
- Huang, Christopher L.-H.;
- Jeevaratnam, Kamalan
Publication type:
Article

Found: 14

Sodium current inhibition following stimulation of exchange protein directly activated by cyclic-3′,5′-adenosine monophosphate (Epac) in murine skeletal muscle.

Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor γ co-activator deficient hearts modelling mitochondrial dysfunction.

Ageing in Pgc-1β<sup>−/−</sup> mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology.

Effects of ageing on pro-arrhythmic ventricular phenotypes in incrementally paced murine Pgc-1β hearts.

The RyR2-P2328S mutation downregulates Na1.5 producing arrhythmic substrate in murine ventricles.

Epac‐induced ryanodine receptor type 2 activation inhibits sodium currents in atrial and ventricular murine cardiomyocytes.

Age‐dependent electrocardiographic changes in Pgc‐1β deficient murine hearts.

Ion channels, long QT syndrome and arrhythmogenesis in ageing.

Reduced cardiomyocyte Na<sup>+</sup> current in the age‐dependent murine Pgc‐1β<sup>−/−</sup> model of ventricular arrhythmia.

Standalone balloon aortic valvuloplasty: Indications and outcomes from the UK in the transcatheter valve era.

Pro-arrhythmic atrial phenotypes in incrementally paced murine Pgc1β<sup>−/−</sup> hearts: effects of age.

Atrial Transcriptional Profiles of Molecular Targets Mediating Electrophysiological Function in Aging and Pgc-1 β Deficient Murine Hearts.

Inhibiting Src family tyrosine kinase activity blocks glutamate signalling to ERK1/2 and Akt/PKB but not JNK in cultured striatal neurones.

Gene and Protein Expression Profile of Selected Molecular Targets Mediating Electrophysiological Function in Pgc-1α Deficient Murine Atria.