We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Facing resistance of H.pylori infection.
- Authors
Zali, Mohammad Reza
- Abstract
Helicobacter pylori is an important human pathogen and a gram-negative, spiral shaped and microaerophilic bacteria with persistence colonization in gastric mucosa, causes gastroduodenal inflammation and destruction, resulting in diseases such as duodenal ulcer disease, gastric ulcer disease. When H.pylori discovered by Warren and Marshall, effective therapy developed for this infection and resulted in remarkable change in management of PUD and dyspepsia. Nowadays, the increasing prevalence of drug resistance has complicated successful therapy, considering more attention for appropriate therapy. Ideally, therapy should be based on pretreatment drug susceptibility testing, and empiric use of eradication therapies should assume the presence of antimicrobial drug resistance and use increased doses for 14 days.
- Subjects
TREATMENT of helicobacter pylori infections; DRUG resistance; ANTI-infective agents; HELICOBACTER pylori; PATHOGENIC bacteria; GASTRIC mucosa; GASTRIC diseases; INDIGESTION
- Publication
Gastroenterology & Hepatology from Bed to Bench, 2011, Vol 4, Issue 1, p3
- ISSN
2008-2258
- Publication type
Article