We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Selected Milestones in Antiviral Drug Development.
- Authors
De Clercq, Erik
- Abstract
This review article will describe the (wide) variety of approaches that I envisaged to develop a specific therapy for viral infections: (i) interferon and its inducers, (ii) HSV, VZV and CMV inhibitors, (iii) NRTIs (nucleoside reverse transcriptase inhibitors), NtRTIs (nucleotide reverse transcriptase inhibitors) and NNRTIs (non-nucleoside reverse transcriptase inhibitors) as HIV inhibitors, (iv) NtRTIs as HBV inhibitors, and finally, (v) the transition of an HIV inhibitor to a stem cell mobilizer, as exemplified by AMD-3100 (Mozobil®).
- Subjects
ANTIVIRAL agents; NUCLEOSIDE reverse transcriptase inhibitors; NON-nucleoside reverse transcriptase inhibitors; DRUG development; REVERSE transcriptase inhibitors; INTERFERON inducers
- Publication
Viruses (1999-4915), 2024, Vol 16, Issue 2, p169
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v16020169