We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Focus Issue: TGF-β and the Mesenchymal Transition in Physiology and Disease.
- Authors
Ferrarelli, Leslie K.; Gough, Nancy R.
- Abstract
The ability of cells to alter their phenotypic and morphological characteristics, known as cellular plasticity, is critical in normal embryonic development and adult tissue repair and contributes to the progression of diseases like organ fibrosis and cancer. Signaling mediated by the transforming growth factor β (TGF-β) superfamily of extracellular protein ligands is one pathway that is integral to these processes. Content published in Science Signaling highlights the roles and complexities of TGF-β signaling in physiology and disease.
- Publication
Science Signaling, 2014, Vol 7, Issue 345, p1
- ISSN
1945-0877
- Publication type
Article
- DOI
10.1126/scisignal.2005909