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- Title
Axillary Regional Recurrence After Sentinel Lymph Node Biopsy for Breast Cancer.
- Authors
Rosing, David K.; Dauphine, Christine E.; Vargas, M. Perla; Gonzalez, Katherine; Burla, Melissa; Kaufmann, Paul; Vargas, Hernan I.
- Abstract
The accuracy of sentinel lymph node biopsy (SLNB) staging in breast cancer has been demonstrated in studies comparing it with axillary dissection. There is a 5 per cent false-negative rate, but this does not always correlate with axillary recurrence. Our purpose was to determine the rate of axillary lymphatic recurrence in breast cancer patients who had a negative SLNB. We conducted a cohort study of breast cancer patients who underwent SLNB between 2001 and 2005. Only patients who had a negative SLNB were included. Patient demographics and tumor factors were reviewed. Outcomes measured were axillary and systemic recurrence and survival. Eighty-nine patients with a mean age of 54.4 ± 9.9 years were included. Eighty-nine per cent of cases had infiltrating ductal carcinoma histology. Mean tumor size was 19 ± 14 mm. Breast conservation surgery was done in 65 cases and mastectomy in 24. A mean of 2.3 ± 2.4 SLN were found. After a median follow-up of 2.15 years, 1 (1%) patient developed a lymphatic recurrence in the axilla. SLNB provides accurate staging of breast cancer. Patients with negative SLNB do not require axillary dissection.
- Subjects
LYMPH nodes; BIOPSY; BREAST cancer; CANCER patients; DEMOGRAPHY; SURGERY
- Publication
American Surgeon, 2006, Vol 72, Issue 10, p939
- ISSN
0003-1348
- Publication type
Article
- DOI
10.1177/000313480607201022