We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Clopidogrel, CYP2C19 and proton pump inhibitors: What we know and what it means.
- Authors
Hariharan, Sudharshan; Southworth, Mary Ross; Madabushi, Rajanikanth
- Abstract
The article presents authors' views on their study findings related to the role of cytochrome P450 2C19 (CYP2C19) in bioactivation pathway of antiplatelet agent clopidogrel, which was published in the August 2014 issue of the periodical. Topics discussed include the complexities associated with metabolic pathway of clopidogrel, drug interactions between clopidogrel and CYP2C19 and use of proton pump inhibitors to minimize antiplatelet treatment for gastrointestinal bleeding.
- Subjects
PROTON pump inhibitors; CLOPIDOGREL
- Publication
Journal of Clinical Pharmacology, 2014, Vol 54, Issue 8, p884
- ISSN
0091-2700
- Publication type
Article
- DOI
10.1002/jcph.337