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- Title
Fitness, work, and leisure-time physical activity and ischaemic heart disease and all-cause mortality among men with pre-existing cardiovascular disease.
- Authors
Holtermann, Andreas; Mortensen, Ole Steen; Burr, Hermann; Søgaard, Karen; Gyntelberg, Finn; Suadicani, Poul
- Abstract
Objective Our aim was to study the relative impact of physical fitness, physical demands at work, and physical activity during leisure time on ischaemic heart disease (IHD) and all-cause mortality among employed men with pre-existing cardiovascular disease (CVD). Method We carried out a 30-year follow-up of the Copenhagen Male Study of 274 gainfully employed men, aged 40-59 years who had a history of CVD (ie, myocardial infarction, angina pectoris, and intermittent claudication). We estimated physical fitness [maximal oxygen consumption (VO2Max)] using the Åstrand cycling test and determined physical work demands and leisure-time physical activity using a self-reported questionnaire. Results Among 274 men with a history of CVD, 93 men died from IHD. Using male employees with a history of CVD and a low level of fitness as the reference group, our Cox analyses - adjusted for age, blood pressure, smoking, alcohol consumption, body mass index, diabetes, hypertension, physical work demands, leisure-time physical activity, and social class - showed a substantially reduced risk for IHD mortality among employees who were intermediately fit [VO2Max range 25-36; hazard ratio (HR) 0.54, 95% confidence interval (95% CI) CI 0.32-0.93] and highly fit (VO2Max range 37-50; HR 0.28, 95% CI 0.12-0.66). We found a positive, but statistically non-significant association between physical demands at work and all-cause mortality. Conclusion Among gainfully employed men with pre-existing CVD, a high physical fitness was associated with a substantially reduced risk for IHD and all-cause mortality.
- Subjects
ISCHEMIA; CARDIOVASCULAR diseases; PHYSICAL fitness; OXYGEN consumption; BLOOD pressure
- Publication
Scandinavian Journal of Work, Environment & Health, 2010, Vol 36, Issue 5, p366
- ISSN
0355-3140
- Publication type
Article
- DOI
10.5271/sjweh.2914