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- Title
Anaerobic biodegradation of spiramycin I and characterization of its new metabolites.
- Authors
Yao, Jian; Shao, Lei; Chen, Daijie; Liu, Pengyu; Zhang, Yubin
- Abstract
Activated sludge was used to treat the wastewater containing spiramycin I. Three new metabolites were isolated and identified, which produced by oxidation of C6-aldehyde, hydrolysis of C5-mycaminose-mycarose and macrolactone ring-open reaction of spiramycin I in anaerobic digestion. And their antimicrobial activities were inactivated. Our results indicated that anaerobic biodegradation metabolites of spiramycin I could not induce bacterial resistance in environment.
- Subjects
SPIRAMYCIN; METABOLITE analysis; HYDROLYSIS kinetics
- Publication
Bioscience, Biotechnology & Biochemistry, 2017, Vol 81, Issue 5, p1051
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1080/09168451.2017.1281003