We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Intra-operative cisplatin for the treatment of canine extremity soft tissue sarcomas.
- Authors
Havlicek, M.; Straw, R. S.; Langova, V.; Dernell, W. S.
- Abstract
Nineteen dogs with histologically confirmed soft tissue sarcomas of the extremities were treated with a combination of marginal surgery and intra-operative chemotherapy in the form of cisplatin in a biodegradable implant delivery system (Atrigel®; Atrix Laboratories, Fort Collins, Co, USA). None of the dogs had evidence of metastasis at time of treatment. The median dose of cisplatin was 52.1 mg/m2 (mean 55.4 mg/m2, range 18.5–108.6 mg/m2). Wound complications were noted in 16 dogs (84.2%). Median follow-up time was 874 days (mean 777 days, range 125–1463 days). Nine dogs (47.3%) were alive at the time of analysis. Local recurrence occurred in three dogs (16.6%). The time to recurrence was 214, 264 and 874 days.
- Subjects
CISPLATIN; SOFT tissue tumors; SARCOMA; DOG diseases; DRUG therapy; TUMOR treatment
- Publication
Veterinary & Comparative Oncology, 2009, Vol 7, Issue 2, p122
- ISSN
1476-5810
- Publication type
Article
- DOI
10.1111/j.1476-5829.2009.00182.x