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- Title
Combination of antidepressant drugs: the case of inositol.
- Authors
Nemets, Boris; Mendel, Fux; Levine, Joseph; Belmaker, R. H.
- Abstract
Inositol is a second messenger precursor that is effective in depression and obsessive-compulsive disorder via a mechanism different from serotonin reuptake inhibitors. However, controlled trials of inositol combined with serotonin reuptake inhibitors in depression or in reuptake inhibitor resistant depressed patients, or in partially responsive obsessive-compulsive patients, did not reveal added benefit. This is comparable to results with combinations of other antidepressant treatments, such as tricyclics plus monoamine oxidase inhibitors. Copyright © 2001 John Wiley & Sons, Ltd.
- Subjects
ANTIDEPRESSANTS; INOSITOL; OBSESSIVE-compulsive disorder; MONOAMINE oxidase inhibitors; SEROTONIN uptake inhibitors; MENTAL depression
- Publication
Human Psychopharmacology: Clinical & Experimental, 2001, Vol 16, Issue 1, p37
- ISSN
0885-6222
- Publication type
Article
- DOI
10.1002/hup.181