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Targeting vasoactive intestinal peptide-mediated signaling enhances response to immune checkpoint therapy in pancreatic ductal adenocarcinoma.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34242-4
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- Publication type:
- Article
The tumor microenvironment in pancreatic ductal adenocarcinoma: current perspectives and future directions.
- Published in:
- Cancer & Metastasis Reviews, 2021, v. 40, n. 3, p. 675, doi. 10.1007/s10555-021-09988-w
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- Publication type:
- Article
Pepinemab (Anti-SEMA4D) in Combination with Ipilimumab or Nivolumab for Patients with Resectable Pancreatic and Colorectal Cancer.
- Published in:
- 2021
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- Publication type:
- Letter
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells.
- Published in:
- Molecular Cancer, 2010, v. 9, p. 217, doi. 10.1186/1476-4598-9-217
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- Publication type:
- Article
The small molecule curcumin analog FLLL32induces apoptosis in melanoma cells via STAT3inhibition and retains the cellular response tocytokines with anti-tumor activity.
- Published in:
- Molecular Cancer, 2010, v. 9, p. 165, doi. 10.1186/1476-4598-9-165
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- Publication type:
- Article
The Potential of CAR T Cell Therapy in Pancreatic Cancer.
- Published in:
- Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02166
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- Publication type:
- Article
Novel Small Molecule XPO1/CRM1 Inhibitors Induce Nuclear Accumulation of TP53, Phosphorylated MAPK and Apoptosis in Human Melanoma Cells.
- Published in:
- PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102983
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- Publication type:
- Article
PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27<sup>Kip1</sup>.
- Published in:
- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074710
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- Publication type:
- Article
Structurally Modified Curcumin Analogs Inhibit STAT3 Phosphorylation and Promote Apoptosis of Human Renal Cell Carcinoma and Melanoma Cell Lines.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0040724
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- Publication type:
- Article
Modulation of the tumor microenvironment by armed vesicular stomatitis virus in a syngeneic pancreatic cancer model.
- Published in:
- Virology Journal, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12985-022-01757-7
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- Publication type:
- Article
A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186.
- Published in:
- Cancer Immunology, Immunotherapy, 2021, v. 70, n. 11, p. 3337, doi. 10.1007/s00262-021-02986-5
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- Publication type:
- Article
Bortezomib pre-treatment prolongs interferon-alpha-induced STAT1 phosphorylation in melanoma cells.
- Published in:
- Cancer Immunology, Immunotherapy, 2009, v. 58, n. 12, p. 2031, doi. 10.1007/s00262-009-0710-y
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- Publication type:
- Article
Activation of extracellular signaling regulated kinase in natural killer cells and monocytes following IL-2 stimulation in vitro and in patients undergoing IL-2 immunotherapy: analysis via dual parameter flow-cytometric assay.
- Published in:
- Cancer Immunology, Immunotherapy, 2008, v. 57, n. 8, p. 1137, doi. 10.1007/s00262-007-0444-7
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- Publication type:
- Article
STAT1-dependent and STAT1-independent gene expression in murine immune cells following stimulation with interferon-alpha.
- Published in:
- Cancer Immunology, Immunotherapy, 2007, v. 56, n. 11, p. 1845, doi. 10.1007/s00262-007-0329-9
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- Publication type:
- Article
Expression of STAT1 and STAT2 in malignant melanoma does not correlate with response to interferon-alpha adjuvant therapy.
- Published in:
- Cancer Immunology, Immunotherapy, 2005, v. 54, n. 9, p. 815, doi. 10.1007/s00262-004-0649-y
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- Publication type:
- Article
Multiparametric flow cytometric analysis of inter-patient variation in STAT1 phosphorylation following interferon Alfa immunotherapy.
- Published in:
- 2004
- By:
- Publication type:
- journal article
STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer.
- Published in:
- Life Science Alliance, 2022, v. 5, n. 11, p. 1, doi. 10.26508/lsa.202201460
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- Publication type:
- Article
MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity.
- Published in:
- PLoS ONE, 2019, v. 14, n. 10, p. 1, doi. 10.1371/journal.pone.0224600
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- Publication type:
- Article
Perspectives in Immunotherapy: meeting report from Immunotherapy Bridge (Naples, November 30th–December 1st, 2022).
- Published in:
- Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04117-3
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- Publication type:
- Article
UV Light B-Mediated Inhibition of Skin Catalase Activity Promotes Gr-1<sup>+</sup>CD11b<sup>+</sup> Myeloid Cell Expansion.
- Published in:
- Journal of Investigative Dermatology, 2012, v. 132, n. 3 part 1, p. 695, doi. 10.1038/jid.2011.329
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- Publication type:
- Article
Immune checkpoint inhibitors for the treatment of MSI-H/MMR-D colorectal cancer and a perspective on resistance mechanisms.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Impact of nodal status in determining multimodal treatment strategies in non‐cardia gastric cancer.
- Published in:
- Journal of Surgical Oncology, 2023, v. 128, n. 2, p. 242, doi. 10.1002/jso.27297
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- Publication type:
- Article
A dose-finding and pharmacodynamic study of bortezomib in combination with weekly paclitaxel in patients with advanced solid tumors.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 1, p. 151, doi. 10.1007/s00280-009-1145-z
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- Publication type:
- Article
A dose-finding and pharmacodynamic study of bortezomib in combination with weekly paclitaxel in patients with advanced solid tumors.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Inhibition of HSP90 overcomes resistance to chemotherapy and radiotherapy in pancreatic cancer.
- Published in:
- International Journal of Cancer, 2019, v. 145, n. 6, p. 1529, doi. 10.1002/ijc.32227
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- Publication type:
- Article
Suppressive myeloid cells are expanded by biliary tract cancer-derived cytokines in vitro and associate with aggressive disease.
- Published in:
- 2020
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- Publication type:
- journal article
Release of Biologically Functional Interferon-Alpha from a Nanochannel Delivery System.
- Published in:
- Biomedical Microdevices, 2005, v. 7, n. 1, p. 71, doi. 10.1007/s10544-005-6174-8
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- Publication type:
- Article
Intestinal Microbial Dysbiosis and Colonic Epithelial Cell Hyperproliferation by Dietary α-Mangostin is Independent of Mouse Strain.
- Published in:
- 2015
- By:
- Publication type:
- Journal Article
Combined IL6 and CCR2 blockade potentiates antitumor activity of NK cells in HPV-negative head and neck cancer.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-024-03002-1
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- Publication type:
- Article
Targeted Therapies: Immunologic Effects and Potential Applications Outside of Cancer.
- Published in:
- Journal of Clinical Pharmacology, 2018, v. 58, n. 1, p. 7, doi. 10.1002/jcph.1028
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- Publication type:
- Article
Inhibiting heat shock protein 90 and the ubiquitin-proteasome pathway impairs metabolic homeostasis and leads to cell death in human pancreatic cancer cells.
- Published in:
- 2017
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- Publication type:
- journal article
Mismatch Repair (MMR) Gene Alteration and BRAF V600E Mutation Are Potential Predictive Biomarkers of Immune Checkpoint Inhibitors in MMR‐Deficient Colorectal Cancer.
- Published in:
- Oncologist, 2021, v. 26, n. 8, p. 668, doi. 10.1002/onco.13741
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- Publication type:
- Article
Soy isoflavones and their metabolites modulate cytokine-induced natural killer cell function.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-41687-z
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- Publication type:
- Article
Circulating monocyte chemoattractant protein‐1 (MCP‐1) is associated with cachexia in treatment‐naïve pancreatic cancer patients.
- Published in:
- Journal of Cachexia, Sarcopenia & Muscle, 2018, v. 9, n. 2, p. 358, doi. 10.1002/jcsm.12251
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- Publication type:
- Article
MicroRNA profiling of patient plasma for clinical trials using bioinformatics and biostatistical approaches.
- Published in:
- OncoTargets & Therapy, 2016, v. 9, p. 5931, doi. 10.2147/OTT.S106288
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- Publication type:
- Article
Enhanced bioavailability of lycopene when consumed as cis-isomers from tangerine compared to red tomato juice, a randomized, cross-over clinical trial.
- Published in:
- Molecular Nutrition & Food Research, 2015, v. 59, n. 4, p. 658, doi. 10.1002/mnfr.201400658
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- Publication type:
- Article
Dietary α-mangostin, a xanthone from mangosteen fruit, exacerbates experimental colitis and promotes dysbiosis in mice.
- Published in:
- Molecular Nutrition & Food Research, 2014, v. 58, n. 6, p. 1226, doi. 10.1002/mnfr.201300771
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- Publication type:
- Article
Top advances of the year: Pancreatic cancer.
- Published in:
- Cancer (0008543X), 2023, v. 129, n. 24, p. 3843, doi. 10.1002/cncr.35031
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- Publication type:
- Article
Napabucasin (BBI 608), a potent chemoradiosensitizer in rectal cancer.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia.
- Published in:
- 2015
- By:
- Publication type:
- journal article
Short-Term Soy Bread Intervention Leads to a Dose-Response Increase in Urinary Isoflavone Metabolites and Satiety in Chronic Pancreatitis.
- Published in:
- Foods, 2023, v. 12, n. 9, p. 1762, doi. 10.3390/foods12091762
- By:
- Publication type:
- Article
Modulation of SOCS protein expressioninfluences the interferon responsiveness ofhuman melanoma cells.
- Published in:
- BMC Cancer, 2010, v. 10, p. 142, doi. 10.1186/1471-2407-10-142
- By:
- Publication type:
- Article