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- Title
Charakterisierung hämopoetischer Stamm- und Vorläuferzellen: Zellkultur und Multiparameter-Durchflußzytometrie.
- Authors
Serke, S.; Schneider, Ulrike
- Abstract
According to retrospective analysis, the length of the hemopoietic recovery-time after transplantation is correlated to the number of transplanted hemopoietic cells. For this reason there is a need for proper determination of these cells prior to transplantation. Cell-cultures as well as multiparameter flow-cytometry are suitable methods. While the various hematopoietic cells differ with regard to optimal culture conditions, flow-cytometry takes advantage of the fact that all hematopoietic cells are expressing the CD34 antigen. Differential co-expression of differentiation-antigens allows for sub-dissection of CD34-expressing cells into stem- and progenitor-cells. This report decribes the features of the various hemopoietic stem- and progenitor-cells.
- Publication
Journal of Laboratory Medicine / Laboratoriums Medizin, 1996, Vol 20, Issue 5, p262
- ISSN
0342-3026
- Publication type
Article