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- Title
Cardiac factors affecting the success of vardenafil in erectile dysfunction.
- Authors
ZENGİN, Kürşad; EDE, Hüseyin; TANIK, Serhat; ALBAYRAK, Sebahattin; SARIKAYA, Savaş; ERBAY, Alirıza; İMAMOĞLU, Muhammet Abdurrahim; GÜRDAL, Mesut
- Abstract
Background/aim: To evaluate the predictability of vardenafil success in patients with erectile dysfunction (ED) by using cardiological tests. Materials and methods: Patients diagnosed with ED who did not benefit from lifestyle changes (n = 68) were evaluated with an abridged 5-item version of the International Index of Erectile Function (IIEF-5). The pretreatment and posttreatment IIEF-5 scores were compared with pretreatment data obtained from cardiological examinations. Results: When pretreatment scores were compared with test parameters, mitral flow E/A ratio and tissue Doppler imaging (TDI) E'/ A', exercise test duration, exercise capacity in MET, and percentage of maximum heart rate were found to be statistically significant. Furthermore, there was a significant negative correlation between mitral flow E/A ratio, TDI E'/A', exercise test duration, exercise capacity in MET, and the difference in post- and pretreatment IIEF-5 scores. Conclusion: As a diastolic function indicator, TDI E'/A' positively correlates with pretreatment IIEF-5 scores and negatively correlates with the beneficial effect of vardenafil treatment. As a result, the cardiological status of the patient correlates with individual IIEF-5 scores, and it seems to be useful in predicting vardenafil success.
- Subjects
VARDENAFIL; IMPOTENCE; PHOSPHODIESTERASE-5 inhibitors; COMPARATIVE studies; STATISTICAL correlation; DIAGNOSIS; PATIENTS
- Publication
Turkish Journal of Medical Sciences, 2015, Vol 45, Issue 4, p751
- ISSN
1300-0144
- Publication type
Article
- DOI
10.3906/sag-1407-69