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- Title
EXFOLIATIVE CYTOLOGICAL FINDINGS IN ORAL POTENTIALLY MALIGNANT DISORDERS.
- Authors
Waris, Mehwish; Ahmad, Sajjad; Khan, Muhammad Mumtaz; Nasir, Sabeen; Mushtaq, Qurat-Ul-Ain; Taj, Farooq
- Abstract
Objective: Patients with oral potentially malignant disorders (OPMDs) are at risk for development of malignancy. This study was designed to assess the dysplastic changes in oral exfoliative cytological specimens from OPMD cases thus screening patients who may need biopsy for evaluation and progression of their lesion. Materials and Methods: This descriptive cross-sectional study was conducted at Histopathology Laboratory of Peshawar Medical College, Peshawar for which samples were collected from two dental hospitals and private dental clinics of Peshawar. The study included 20 cases of clinically diagnosed Oral Potentially Malignant Disorders (OPMDs); including 10 cases of leukoplakia and 10 cases of oral lichen planus (OLP), and 20 age and gender matched healthy controls, after observing a strict inclusion and exclusion criteria. A pre-designed proforma was used to collect the data, which was later analyzed in SPSS version 21. Results: A total of 40 participants had a mean age of 48.25±10.01 years with gender distribution of 32(80%) males and 8(20%) females, giving a male to female ratio of 4:1. The duration of OPMD lesions had a mean of 2.3±4.4 years. On Oral Exfoliative Cytology (OEC), 10% OPMDs showed atypical changes and 90% showed no such changes, as compared to healthy controls which exhibited a normal cytology without any atypia. As per Oral Bethesda Criteria, 18 (90%) OPMD cases were Negative for Intraepithelial Lesion/Malignancy (NILM) and 2 (10%) showed Low grade Squamous Intraepithelial Lesions (LSIL). Buccal mucosa 12 (60%) was the most common site of lesions. Conclusion: This study concluded that dysplastic cytological findings were seen only in 10% of OPMD cases thus saving majority of the patients from the need to go through the invasive biopsy procedure.
- Subjects
PESHAWAR (Pakistan); EXFOLIATIVE cytology; DENTAL clinics; CYTOLOGY; ORAL lichen planus; MEDICAL schools
- Publication
Journal of Medical Sciences (1997-3438), 2021, Vol 29, Issue 1, p2
- ISSN
1997-3438
- Publication type
Article
- DOI
10.52764/jms.21.29.01.01