We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The enigma of dyspnoea in COPD: A physiological perspective.
- Authors
O'Donnell, Denis E.; Neder, Jose Alberto
- Abstract
Dyspnoea (perceived breathing discomfort) is the most common symptom experienced by patients with chronic obstructive pulmonary disease (COPD) and is associated with progressive physical inactivity and poor quality of life. Exertional dyspnoea ratings in COPD have been shown to consistently correlate with a number of physiological ratios that ultimately point to demand/capacity imbalance of the dynamic respiratory system.[1] These include ventilatory output, tidal oesophageal pressure and tidal diaphragmatic electromyography (EMG) (all expressed relative to respective maxima). Studies using bronchodilators or inspiratory muscle training (IMT) to relive dyspnoea have confirmed the importance of high IND in dyspnoea causation in COPD.
- Subjects
FUNCTIONAL magnetic resonance imaging; PULMONARY gas exchange; HYDROGEN-ion concentration; ENDORPHIN receptors; OBSTRUCTIVE lung diseases
- Publication
Respirology, 2020, Vol 25, Issue 2, p134
- ISSN
1323-7799
- Publication type
Article
- DOI
10.1111/resp.13736