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- Title
State of the Art of Innate Immunity—An Overview.
- Authors
Fischer, Silvia; Deindl, Elisabeth
- Abstract
The concept of PANoptosis, an inflammatory cell death pathway that integrates components of different cell death pathways and is implicated in driving innate immune responses and inflammation, is explained [[6]]. The innate immune system is the first line of defense against bacterial and viral infections and sterile inflammation through the recognition of pathogen-associated molecular patterns (PAMPs) as well as danger-associated molecular patterns (DAMPs) by pathogen-recognition receptors (PRRs), and produces proinflammatory and antiviral cytokines and chemokines [[1]]. Arnholdt et al. demonstrate that cells related to innate immunity and influencing immunoregulatory and inflammatory processes, such as gamma delta T cells, play an important role in angiogenesis and tissue generation.
- Subjects
NATURAL immunity; CELL receptors; ENDOTHELIN receptors; HUMAN cytomegalovirus diseases; TYPE I interferons; CELLULAR recognition; THROMBIN
- Publication
Cells (2073-4409), 2022, Vol 11, Issue 17, p2705
- ISSN
2073-4409
- Publication type
Article
- DOI
10.3390/cells11172705