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- Title
COVID-19 reinfection in the presence of neutralizing antibodies.
- Authors
Zhang, Ju; Ding, Nan; Ren, Lili; Song, Rui; Chen, Danying; Zhao, Xuesen; Chen, Budong; Han, Junyan; Li, Jiarui; Song, Yangzi; Di, Lin; Han, Kai; Yu, Fengting; Xie, Ruming; Chen, Zhihai; Xie, Wen; Liu, Jingyuan; Cen, Shan; Bi, Yuhai; Wu, Angela R
- Abstract
Furthermore, vaccine-induced immunity might be different from natural immunity; vaccines maynotinducethesameTcellresponses as a true SARS-CoV-2 infection does [24].Studieshaveaccumulatedevidence of more broadly dysregulated immune function during viral infection [25], and consistently,wealsoobserveddecreased CD4 + T cell counts in five adult cases, anddecreasedCD8 + Tcellcountsintwo critical COVID-19 patients (Tables S4 and S5). All patients had at least two negative viral RNA tests during the recovered phase between infection periods; two of them (P1 and P2) had 12 and five negative viral RNA tests respectively during thisrecoveredphase(Fig.1a,TableS2). BRIEFCOMMUNICATION NationalScienceReview 8:nwab006,2021 doi:10.1093/nsr/nwab006 Advanceaccesspublication11January2021 CLINICALMEDICINE SpecialSection:SARS-CoV-2 COVID-19 reinfection in the presence of neutralizing antibodies JuZhang 1,2,†,NanDing 1,2,†,LiliRen 3,4,†,RuiSong 1,†,DanyingChen 1,2,†,XuesenZhao 1,2, BudongChen 1,JunyanHan 1,2,JiaruiLi 1,2,YangziSong 1,2,LinDi 5,KaiHan 1,2,FengtingYu 1, RumingXie 1,ZhihaiChen 1,WenXie 1,JingyuanLiu 1,ShanCen 6,YuhaiBi 7,8,AngelaR.Wu 9,*, FujieZhang 1,*,ChenChen 1,2,* andHuiZeng 1,2,* Due to the high transmissibility of the SARS-CoV-2virus,itcontinuestoinfect over 300000 people worldwide per day (WHOstatistics,December2020),even almost one year after the first COVID19 cases were confirmed [ 1,2].
- Subjects
COVID-19; REINFECTION; MEDICAL personnel; CONVALESCENT plasma; IMMUNOGLOBULIN M; IMMUNOGLOBULINS
- Publication
National Science Review, 2021, Vol 8, Issue 4, p1
- ISSN
2095-5138
- Publication type
Article
- DOI
10.1093/nsr/nwab006