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- Title
Structure-Activity Relationships of Glycogen Phosphorylase Inhibitor FR258900 and Its Analogues: A Combined Synthetic, Enzyme Kinetics, and Computational Study.
- Authors
Juhász, László; Varga, Gergely; Sztankovics, Andrea; Béke, Ferenc; Docsa, Tibor; Kiss‐Szikszai, Attila; Gergely, Pál; Kóňa, Juraj; Tvaroška, Igor; Somsák, László
- Abstract
Invited for this month's cover are a group of collaborators from the University of Debrecen (L. Somsák and P. Gergely) and the Institute of Chemistry of the Slovak Academy of Sciences (I. Tvaroška). The cover picture shows the natural product FR258900, some synthetic analogues, and the binding of the most active inhibitor to the allosteric site of the enzyme. Read the full text of the article at
- Subjects
SOMSAK, L.; GERGELY, P.; TVAROSKA, I.; ENZYME analysis; ENZYMES; CHEMICAL synthesis; UNIVERSITY of Debrecen (Debrecen, Hungary); SLOVENSKA akademia vied
- Publication
ChemPlusChem, 2014, Vol 79, Issue 11, p1536
- ISSN
2192-6506
- Publication type
Other
- DOI
10.1002/cplu.201402302