We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Thermally Assisted Electrohydrodynamic Jet High‐Resolution Printing of High‐Molecular Weight Biopolymer 3D Structures.
- Authors
Li, Kai; Wang, Dazhi; Wang, Qiang; Song, Kedong; Liang, Junsheng; Sun, Yulin; Madoua, Marc
- Abstract
High‐molecular biodegradable and bioresorbable polymers are widely used in tissue engineering applications. In this work, a high‐resolution 3D printing technique, thermally assisted electrohydrodynamic jet (TAEJ) printing, is developed for patterning high‐molecular weight biopolymer 3D structures. Boiling point graded polyvinylpyrrolidone (PVP) and PVP/polycaprolactone biopolymer inks are prepared. The resultant effects of electrohydrodynamic force and thermal field are applied on these polymer ink, to form a stable and controllable sub‐micrometer scale jet at the needle tip. Fine jet 2D period patterns and 3D high aspect ratio structures of the biopolymer inks are directly printed using fine jet at a typical feature size of sub‐micrometer. Furthermore, TAEJ printing of 3D heterogeneous high‐molecular weight biopolymer scaffold is demonstrated. Cell culture shows high biocompatibility and cartilage regeneration in vitro, which provides a great potential for tissue engineering applications. Thermally assisted electrohydrodynamic jet (TAEJ) printing is developed for direct writing high‐molecular weight biopolymer sub‐micrometer (700 nm) 2D period patterns and 3D high aspect ratio (15) structures. The printed scaffold exhibits high biocompatibility and cartilage regeneration in vitro. This novel additive manufacturing technique provides a powerful way for tissue engineering applications.
- Subjects
ELECTROHYDRODYNAMICS; MOLECULAR weights; BIOPOLYMERS; BIOCOMPATIBILITY; TISSUE engineering
- Publication
Macromolecular Materials & Engineering, 2018, Vol 303, Issue 11, pN.PAG
- ISSN
1438-7492
- Publication type
Article
- DOI
10.1002/mame.201800345