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- Title
ASSOCIATION ANALYSIS BETWEEN POLYMORPHISM OF STAT5A GENE AND GROWTH TRAITS IN CHINESE GUIZHOU BLACK GOATS.
- Authors
Xie, H. Q.; Sun, Y. Y.; Pan, D. X.; Yang, Y. Q.; Jiao, R. G.; Gong, Y.; Luo, W. X.; Zhang, Y. Y.; Liu, R. Y.
- Abstract
STAT5A gene plays a significant role in growth traits by affecting JAK/STAT pathway. We identified two SNPs which were related to growth traits from 206 healthy and adult purebred individuals of Guizhou Black goats using the methods of direct sequencing and PCR-SSCP. The association analysis between genotypes and growth traits showed that the individuals of genotype TC were superior than CC in chest girth significantly (P<0.05), and the individuals of GA were significant superior than GG and AA in chest girth and body weight (P<0.05). Besides that, the heterozygotes had higher growth traits than those of homozygotes in general. Therefore, we made a conclusion that the two SNPs of STAT5A gene will serve as marker-assisted selection for improving growth traits in goats, but we should still continue to prove the validity of the conclusion by enlarging the total samples and breeds.
- Subjects
CHROMOSOME polymorphism; GENETIC polymorphism research; GOAT genetics; ANIMAL genetics research; LIVESTOCK genetics
- Publication
Pakistan Journal of Agricultural Sciences, 2015, Vol 52, Issue 4, p1119
- ISSN
0552-9034
- Publication type
Article