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- Title
Alcohol Consumption Patterns and Risk of Early-Onset Vasomotor Symptoms in Premenopausal Women.
- Authors
Kwon, Ria; Chang, Yoosoo; Kim, Yejin; Cho, Yoosun; Choi, Hye Rin; Lim, Ga-Young; Kang, Jeonggyu; Kim, Kye-Hyun; Kim, Hoon; Hong, Yun Soo; Park, Jihwan; Zhao, Di; Rampal, Sanjay; Cho, Juhee; Guallar, Eliseo; Park, Hyun-Young; Ryu, Seungho
- Abstract
The role of alcohol consumption in the risk of vasomotor symptoms (VMS), the most cardinal climacteric symptoms, is not well established. We examined their relationship with early-onset VMS among premenopausal women. Moderately-to-severely bothersome VMS, the primary outcome, was assessed using the Korean version of the Menopause-Specific Quality of Life questionnaire. The alcohol consumption categories included lifetime abstainer, former drinker, or current drinker, categorized as light, moderate, heavy, and very heavy. Compared with the lifetime-abstinence (reference), the multivariable-adjusted odds ratio (95% CIs) for prevalent VMS in alcohol consumption of <10, 10–19, 20–39, and ≥40 g/day were 1.42 (1.02–1.99), 1.99 (1.27–3.12), 2.06 (1.19–3.57), and 3.52 (1.72–7.20), respectively (p trend <0.01). Compared with the lifetime-abstinence, the multivariable-adjusted hazard ratios (95% CIs) for incident bothersome VMS among average alcohol consumption of <10, 10–19, 20–39, and ≥40 g/day were 1.10 (0.85–1.41), 1.03 (0.70–1.51), 1.72 (1.06–2.78), and 2.22 (1.16–4.23), respectively (p trend = 0.02). Increased alcohol consumption positively and consistently showed a relationship with increased risk of both prevalent and incident early-onset VMS. Refraining from alcohol consumption may help prevent bothersome VMS in premenopausal women.
- Subjects
PERIMENOPAUSE; CONFIDENCE intervals; MULTIVARIATE analysis; WOMEN; RISK assessment; TEMPERANCE; ALCOHOL drinking; AGE factors in disease; QUESTIONNAIRES; DESCRIPTIVE statistics; DISEASE prevalence; HEALTH behavior; ODDS ratio
- Publication
Nutrients, 2022, Vol 14, Issue 11, p2276
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu14112276