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- Title
Acquired hemophilia A in a case of purple urine bag syndrome.
- Authors
Gammaldi, Vittoria; Guida, Anna; Bologna, Carolina; De Sena, Antonietta; Lugarà, Marina; De Luca, Claudio; Granato Corigliano, Fabio; Guerra, Mariavittoria; Oliva, Gabriella; Mocerino, Luca; Zarrella, Aquilino Flavio; Coppola, Maria Gabriella; Nuzzo, Vincenzo; Tirelli, Paolo; Madonna, Pasquale
- Abstract
The rare hemorrhagic disorder known as acquired hemophilia A (AHA) is brought on by the spontaneous development of autoantibodies against coagulation factor VIII (FVIII). It may be secondary to autoimmune diseases or cancers, or it may be idiopathic. Less than 10% of cases may have an infection as a secondary cause. We present the case of a 90-year-old anemic woman who was admitted to the hospital. She contracted a urinary tract infection (UTI) while in the hospital, and her urine took on a distinct purple hue. She had poor hemorrhagic manifestations and a prolonged partial thromboplastin time. After ruling out autoimmune and neoplastic causes, we diagnosed AHA as a result of a UTI caused by Enterococcus faecalis.
- Subjects
HEMOPHILIA; URINARY tract infections; URINE; HEMORRHAGIC diseases; BLOOD coagulation factors; BLOOD coagulation factor VIII
- Publication
Italian Journal of Medicine, 2024, Vol 18, Issue 2, p1
- ISSN
1877-9344
- Publication type
Article
- DOI
10.4081/itjm.2024.1713