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- Title
DELIVERY OF NEBIVOLOL HYDROCHLORIDE FROM IMMEDIATE RELEASE TABLETS.
- Authors
Khalaf, Zahraa; Ardelean, Simona; Drăgănescu, Doina; Ardelean, Monica; Lupuleasa, Dumitru
- Abstract
The paper presents the results of our study regarding 9 formulations with nebivolol 10 mg with immediate release. The solubility of nebivolol hydrochloride was determined in various aqueous solutions and buffer (HCl pH=2). The solubility study was conducted by taking excess amounts of the drug in solution. In vitro dissolution profiles showed a rapid release, approaching 10% of the declared content of nebivolol hydrochloride, towards the end of the test period.
- Subjects
NEBIVOLOL hydrochloride; DRUG administration; DISSOLUTION (Chemistry); AQUEOUS solutions; BUFFER solutions
- Publication
Studia Universitatis Vasile Goldis Seria Stiintele Vietii (Life Sciences Series), 2015, Vol 25, Issue 1, p47
- ISSN
1584-2363
- Publication type
Article