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- Title
Cervical section of vagus nerve and loss of weight in rats.
- Authors
Luz de la Cruz-Aguilera, Dora; Calleja, Juan; MartÃnez, Adrián; Morales-Espinoza, Gabriel; Pellicer, Francisco; Aguirre-Cruz, Lucinda
- Abstract
Objectives: to evaluate the effect of cervical vagotomy on the weight of rats with and without cardiac puncture. Material and methods: eighty male Wistar rats, weighing 250-300 g were divided into four groups (n = 20). In rats from Group A, a midline incision of 2 cm in the anterior neck, identification and section of the vagus nerve were made; in those from Group B (sham), the vagus nerve was exposed, but it was no sectioned; the rats from Groups C (with cardiac puncture) and D (without cardiac puncture) were no operated (controls without surgical intervention). Then, all animals except those of the Group D, were blooded by cardiac puncture before the vagotomy and in the 21st post-operatory (PO) day. The weight of all rats was registered before making the vagotomy (day 0), everyday from the 1st to 7th, the 14th and the 21st PO days. The weight of vagotomized animals was significantly lower than that in non-vagotomized animals, only in the first PO day (p < 0.05). The weight of rats with and without cardiac puncture was similar. Conclusions: the cervical vagotomy associates to a loss of weight in rats, only in the first 24 h of the PO period. The cardiac puncture does not cause variations of weight in rats with or without vagotomy.
- Publication
Archivos de Neurociencias, 2011, Vol 16, Issue 3, p136
- ISSN
1028-5938
- Publication type
Journal Article