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- Title
Urine Tenofovir Levels Strongly Correlate With Virologic Suppression in Patients With Human Immunodeficiency Virus on Tenofovir Alafenamide-Based Antiretroviral Therapy.
- Authors
Johnson, Kelly A; Okochi, Hideaki; Arreguin, Mireya; Watabe, Joseph; Glidden, David V; Chattopadhyay, Anindita; Imbert, Elizabeth; Hickey, Matthew D; Gandhi, Monica; Spinelli, Matthew
- Abstract
We found that urine tenofovir (TFV) levels >1500 ng/mL strongly predict virologic suppression among people with human immunodeficiency virus taking tenofovir alafenamide (odds ratio, 5.66; 95% confidence interval, 1.59–20.14; P =.007). This suggests an existing point-of-care assay developed for tenofovir disoproxil fumarate will support adherence monitoring for patients on all TFV-based antiretrovirals.
- Subjects
HIV-positive persons; HIV infections; CONFIDENCE intervals; TENOFOVIR; VIRAL load; POINT-of-care testing; ANTIRETROVIRAL agents; DESCRIPTIVE statistics; DRUGS; DRUG monitoring; RESEARCH funding; ODDS ratio; PATIENT compliance
- Publication
Clinical Infectious Diseases, 2023, Vol 76, Issue 5, p930
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciac828