We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
PNEUMONIA MASIVĂ ŞI PANCITOPENIA CONDUC LA DIAGNOSTICUL DE LEUCEMIE ACUTĂ LIMFOBLASTICĂ LA COPIL - PREZENTARE DE CAZ ŞI DATE DIN LITERATURĂ.
- Authors
Melit, Lorena Elena; Margi, Cristina Oana; Chincesan, Mihaela Ioana; Armean, Iulia; Sasaran, Vladut Stefanut; Marginean, Maria Oana
- Abstract
Acute lymphoblastic leukemia (ALL) is one of the most common type of malignancies in children, but at the same time one of the cancers with the best prognostic. Transient pancytopenia has been described to be a very rare entity defined as a preleukemic condition in children and adolescents. We present the case of a 2-year-old male, with a 2-week history of respiratory tract infection, without any improvement after antibiotic therapy, admitted in our clinic with fever, influenced general status, productive cough, intense pallor, palpebral edema and perianal abscess. The laboratory findings revealed severe anemia, mild leukopenia and increased inflammatory biomarkers. The thoracic radiography pointed out a massive right pneumonia. The child was discharge after 3 weeks of wide spectrum antibiotics, presenting a favorable evolution. The follow-up CBC count at approximately 2 weeks from discharge revealed severe leukocytosis, and the immunophenotyping exam of the bone marrow established the diagnosis of pre-B cell type acute lymphoblastic leukemia. All patients treated for pancytopenia must benefit by a proper long-term monitoring in order to rule out the afterwards development of a potential ALL.
- Subjects
LYMPHOBLASTIC leukemia in children; PANCYTOPENIA; IMMUNOPHENOTYPING; ANTIBIOTICS; LEUCOCYTOSIS
- Publication
Romanian Journal of Pediatrics / Revista Romana de Pediatrie, 2017, Vol 66, Issue 3, p186
- ISSN
1454-0398
- Publication type
Case Study