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- Title
High-Dose Inhaled Nitric Oxide in Acute Hypoxemic Respiratory Failure due to COVID-19: A Multicenter Phase 2 Trial.
- Authors
Di Fenza, Raffaele; Shetty, Naman S.; Gianni, Stefano; Parcha, Vibhu; Giammatteo, Valentina; Fakhr, Bijan Safaee; Tornberg, Daniel; Wall, Olof; Harbut, Piotr; Lai, Peggy S.; Li, Jonathan Z.; Paganoni, Sabrina; Cenci, Stefano; Mueller, Ariel L.; Houle, Timothy T.; Akeju, Oluwaseun; Bittner, Edward A.; Bose, Somnath; Scott, Louie K.; Carroll, Ryan W.
- Abstract
The article focuses on a multicenter phase 2 trial investigating the use of high-dose inhaled nitric oxide in the treatment of acute hypoxemic respiratory failure due to COVID-19. Topics discussed include the study design, participant criteria, randomization and masking procedures, and the primary and secondary outcomes analyzed using Bayesian estimation.
- Publication
American Journal of Respiratory & Critical Care Medicine, 2023, Vol 208, Issue 12, pE1
- ISSN
1073-449X
- Publication type
Article
- DOI
10.1164/rccm.202304-0637oc