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- Title
The nuclear factor E2-related factor 2 and age-related macular degeneration.
- Authors
de Almeida Torres, Rogil José; de Almeida Torres, Rogério João; Luchini, Andréa; dos Anjos Ferreira, Ana Lúcia
- Abstract
After the discovery of anti-vascular endothelial growth factor agents as treatment of wet age-related macular degeneration, the number of studies with the objective to understand the molecular mechanisms involved in the age-related macular degeneration genesis has increased. The importance of the nuclear factor e2-related factor 2 lies in its activation-derived proteins being involved in the maintenance of the redox balance and consequent prevention of degenerative macular disease. This article aims to present the characteristics of nuclear factor e2-related factor 2 and describe the main nuclear factor e2-related factor 2-activated antioxidant enzymes that contribute to the preservation of vision.
- Subjects
MACULAR degeneration; VASCULAR endothelial growth factor antagonists; PROTHROMBIN; DEGENERATION (Pathology); NUCLEAR factor E2 related factor
- Publication
Arquivos Brasileiros de Oftalmologia, 2023, Vol 86, Issue 2, p178
- ISSN
0004-2749
- Publication type
Article
- DOI
10.5935/0004-2749.20230024