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- Title
Blood Zinc, Iron, and Copper Levels in Critically Ill Neonates.
- Authors
Wang, Guanghuan; Wang, Dian; Jiang, Xuewu; Yu, Xiaojun; Ma, Lian; Zhong, Jun; Feng, Xueyong
- Abstract
The aim of this study is to explore the prognostic value of blood zinc, iron, and copper levels in critically ill neonates by comparing blood metal levels with the score for neonatal acute physiology (SNAP). Forty-six neonates (26 boys, 20 girls; ages ranging from 10 min to 23 days) who had been admitted to the neonatal intensive care unit of hospital and who were critically ill according to SNAP were included. Another 15 neonates (12 boys, 8 girls; ages ranging from 30 min to 24 days) who were brought to the hospital for a health checkup were included as controls. Clinical data, time in the intensive care unit, prognosis, and SNAP for critically ill neonates were recorded. Blood Cu, Zn, and Fe values were measured by inductively coupled plasma atomic emission spectrophotometry. Ill neonates were divided into extremely critical (SNAP ≥10) and critical groups (1 ≤ SNAP < 9). Zn levels were lower in patients than in controls ( p <0.05). Cu levels did not differ between patients and controls ( p >0.05). Fe levels were not significantly between the critical and control groups ( p >0.05). In ill neonates, blood Zn and Fe concentrations in the extremely critical group were lower than in the critical group ( p <0.05). Serious illness in neonates may lead to decreased Zn and Fe blood concentrations. Zn and Fe supplements may be beneficial for critically ill children.
- Subjects
NEONATAL diseases; NEWBORN infant health; CRITICALLY ill; TRANSITION metals; COPPER glazes
- Publication
Biological Trace Element Research, 2015, Vol 164, Issue 1, p8
- ISSN
0163-4984
- Publication type
Article
- DOI
10.1007/s12011-014-0193-3