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- Title
Polishing De Novo Nanopore Assemblies of Bacteria and Eukaryotes With FMLRC2.
- Authors
Mak, Q X Charles; Wick, Ryan R; Holt, James Matthew; Wang, Jeremy R
- Abstract
As the accuracy and throughput of nanopore sequencing improve, it is increasingly common to perform long-read first de novo genome assemblies followed by polishing with accurate short reads. We briefly introduce FMLRC2, the successor to the original FM-index Long Read Corrector (FMLRC), and illustrate its performance as a fast and accurate de novo assembly polisher for both bacterial and eukaryotic genomes.
- Subjects
EUKARYOTIC genomes; BACTERIAL genomes; BACTERIA; GENOMES
- Publication
Molecular Biology & Evolution, 2023, Vol 40, Issue 3, p1
- ISSN
0737-4038
- Publication type
Article
- DOI
10.1093/molbev/msad048