We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Fast and Efficient <sup>18</sup>F-Labeling by [<sup>18</sup>F]Fluorophenylazocarboxylic Esters.
- Authors
Fehler, Stefanie K.; Maschauer, Simone; Höfling, Sarah B.; Bartuschat, Amelie L.; Tschammer, Nuska; Hübner, Harald; Gmeiner, Peter; Prante, Olaf; Heinrich, Markus R.
- Abstract
Introduction of [18F]fluoride ion into the aromatic core of phenylazocarboxylic esters was achieved in only 30 seconds, with radiochemical yields of up to 95 % (85(±10) %). For labeling purposes, the resulting 18F-substituted azoester can be further converted in radical-arylation reactions to give biaryls, or in substitutions at its carbonyl unit to produce azocarboxamides.
- Subjects
FLUORIDES; ESTERS; RADIOCHEMICAL analysis; ARYLATION; CARBONYL compounds
- Publication
Chemistry - A European Journal, 2014, Vol 20, Issue 2, p370
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.201303409