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- Title
Salimabromide: Unexpected Chemistry from the Obligate Marine Myxobacterium Enhygromxya salina.
- Authors
Felder, Stephan; Dreisigacker, Sandra; Kehraus, Stefan; Neu, Edith; Bierbaum, Gabriele; Wright, Patrick R.; Menche, Dirk; Schäberle, Till F.; König, Gabriele M.
- Abstract
Marine myxobacteria ( Enhygromyxa, Plesiocystis, Pseudoenhygromyxa, Haliangium) are phylogenetically distant from their terrestrial counterparts. Salimabromide is the first natural product from the Plesiocystis/ Enhygromyxa clade of obligatory marine myxobacteria. Salimabromide has a new tetracyclic carbon skeleton, comprising a brominated benzene ring, a furano lactone residue, and a cyclohexane ring, bridged by a seven-membered cyclic moiety. The absolute configuration was deduced from experimental and calculated CD data. Salimabromide revealed antibiotic activity towards Arthrobacter cristallopoietes.
- Subjects
MYXOBACTERALES; ARTHROBACTER; CYCLOHEXANE; MOIETIES (Chemistry); ANTIBIOTICS
- Publication
Chemistry - A European Journal, 2013, Vol 19, Issue 28, p9319
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.201301379