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- Title
Description of parallel and sequential configurations for concurrent therapeutic plasma exchange and continuous kidney replacement therapy in adults.
- Authors
Kaushik, Manish; Liew, Zhong Hong; Sewa, Duu‐Wen; Phua, Ghee Chee; Cao, Ling; Krishnamoorthy, Thinesh Lee; Ng, Shin Yi; Lim, Amy Ee Lin; Ng, Li Choo; Koniman, Riece; Teo, Su Hooi; Tan, Han Khim
- Abstract
Therapeutic plasma exchange (TPE) and continuous kidney replacement therapy (CKRT) are extracorporeal therapeutic procedures often implemented in management of patients. Critically ill patients may be afflicted with disease processes that require both TPE and CKRT. Performing TPE discontinuous with CKRT is technically easier, however, it disrupts CKRT and may compromise with CKRT efficiency or hemofilter life. Concurrent TPE with CKRT offers several advantages including simultaneous control of disease process and correction of electrolyte, fluid, and acid‐base disturbances that may accompany TPE. Additionally, TPE may be performed by either centrifugation method or membrane plasma separation method. The technical specifications of these methods may influence the methodology of concurrent connections. This report describes and reviews two different approaches to circuit arrangements when establishing concurrent TPE and CKRT.
- Subjects
PLASMA exchange (Therapeutics); KIDNEY exchange; MEMBRANE separation; THROMBOTIC thrombocytopenic purpura; ADULTS
- Publication
Journal of Clinical Apheresis, 2021, Vol 36, Issue 1, p211
- ISSN
0733-2459
- Publication type
Article
- DOI
10.1002/jca.21854