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- Title
Accelerated MRI of the Lumbar Spine Using Compressed Sensing: Quality and Efficiency.
- Authors
Bratke, Grischa; Rau, Robert; Weiss, Kilian; Kabbasch, Christoph; Sircar, Krishnan; Morelli, John N; Persigehl, Thorsten; Maintz, David; Giese, Daniel; Haneder, Stefan
- Abstract
<bold>Background: </bold>Decreasing MRI scan time is a key factor to increase patient comfort and compliance as well as the productivity of MRI scanners.<bold>Purpose/hypothesis: </bold>Compressed sensing (CS) should significantly accelerate 3D scans. This study evaluated the clinical application and cost effectiveness of accelerated 3D T2 sequences of the lumbar spine.<bold>Study Type: </bold>Prospective, cross-sectional, observational.<bold>Population: </bold>Twenty healthy volunteers and 10 patients.<bold>Field Strength/sequence: </bold>A 3D T2 TSE sequence, identical 3D sequences with three different parallel imaging and CS accelerating factors, and 2D TSE sequences as a clinical reference were obtained on a 3T scanner.<bold>Assessment: </bold>Three readers evaluated the sequences for delineation of anatomical structures and image quality. A quantitative analysis consisting of root mean square error, structural similarity index, signal-to-noise ratio, and contrast-to-noise ratio were performed. The scan times were used to calculate cost differences for each sequence.<bold>Statistical Tests: </bold>An analysis of variance with repeated measurements and the Friedman test were used to test for potential differences between the sequences. Post-hoc analysis was made with the chi-squared and Tukey-Kramer test.<bold>Results: </bold>CS with factor 4.5 results in unchanged image quality compared to the T2 TSE for volunteers and patients (overall image impression: 4.75 vs. 4.20 [P = 0.73] and 4.90 vs. 4.47 [P = 0.44]). The CS 4.5 scan is 167 seconds (-39%) faster than the 3D and 216.5 seconds (-45%) faster than the 2D sequences. No significant differences was found for the diagnostic certainty in the volunteers and patients between 2D TSE and 3D CS 4.5 (P = 0.89 and P = 0.43). A reduction of scan time to 148 seconds (CS 8) was still rated acceptable for most diagnosis.<bold>Data Conclusion: </bold>CS accelerates the 3D T2 without compromising image quality. The 3D sequences offer comparable diagnostic quality to the clinical 2D standard with less scan time (-45%), potentially increasing the productivity of MRI scanners.<bold>Level Of Evidence: </bold>1 Technical Efficacy: Stage 6 J. Magn. Reson. Imaging 2019;49:e164-e175.
- Subjects
COMPUTERS in medicine; DIGITAL image processing; THREE-dimensional imaging; MOTION; CROSS-sectional method; MAGNETIC resonance imaging; DIAGNOSTIC imaging; COST effectiveness; LUMBAR vertebrae; MEDICAL artifacts; LONGITUDINAL method
- Publication
Journal of Magnetic Resonance Imaging, 2019, Vol 49, Issue 6, pe164
- ISSN
1053-1807
- Publication type
journal article
- DOI
10.1002/jmri.26526