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- Title
Spiculisporic Acids B--D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2.
- Authors
Rong Wang; Tian-Mi Liu; Ming-Hui Shen; Ming-Qiu Yang; Quan-Ying Feng; Xian-Ming Tang; Xiang-Min Li
- Abstract
Three new γ-butenolide derivatives 1-3, named spiculisporic acids B-D, were isolated from the culture of Aspergillus sp. HDf2, a marine-derived fungus that resides in the sea urchin, Anthocidaris crassispina. The structures of 1-3 were elucidated on the basis of spectroscopic methods, including MS and 2D NMR techniques. Their in vitro cytotoxic activities against two cell lines (SGC-7901, human gastric adenocarcinoma and SPC-A-1, human lung adenocarcinoma) and inhibitory activities against Staphylococcus aureus ATCC 51650 were investigated
- Subjects
FUNGAL metabolism; BUTENOLIDES; ASPERGILLUS; SEA urchins; ACID derivatives; CELL-mediated cytotoxicity; CELL lines
- Publication
Molecules, 2012, Vol 17, Issue 11, p13175
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules171113175