The article presents research highlights based on the original research paper "Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice," by J. Qing et al. that appeared in issue 119, 2009 of the "Journal of Clinical Investigation." Subjects discussed include the overexpression of fibroblast growth factor receptor 3 (FGFR3), tumorigenesis, and bladder cancer.