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- Title
Recent Advances in Pharmaceutical Approaches of Antimicrobial Agents for Selective Delivery in Various Administration Routes.
- Authors
Marzaman, Ardiyah Nurul Fitri; Roska, Tri Puspita; Sartini, Sartini; Utami, Rifka Nurul; Sulistiawati, Sulistiawati; Enggi, Cindy Kristina; Manggau, Marianti A.; Rahman, Latifah; Shastri, Venkatram Prasad; Permana, Andi Dian
- Abstract
Globally, the increase of pathogenic bacteria with antibiotic-resistant characteristics has become a critical challenge in medical treatment. The misuse of conventional antibiotics to treat an infectious disease often results in increased resistance and a scarcity of effective antimicrobials to be used in the future against the organisms. Here, we discuss the rise of antimicrobial resistance (AMR) and the need to combat it through the discovery of new synthetic or naturally occurring antibacterial compounds, as well as insights into the application of various drug delivery approaches delivered via various routes compared to conventional delivery systems. AMR-related infectious diseases are also discussed, as is the efficiency of various delivery systems. Future considerations in developing highly effective antimicrobial delivery devices to address antibiotic resistance are also presented here, especially on the smart delivery system of antibiotics.
- Subjects
ANTI-infective agents; DRUG resistance in bacteria; DRUG resistance in microorganisms; PATHOGENIC bacteria; COMMUNICABLE diseases; TARGETED drug delivery
- Publication
Antibiotics (2079-6382), 2023, Vol 12, Issue 5, p822
- ISSN
2079-6382
- Publication type
Article
- DOI
10.3390/antibiotics12050822