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- Title
Atypical stromal herpes simplex keratitis: clinical features and diagnosis.
- Authors
Qiu, Ji-ni; Huang, Fei-fei; Liu, Chun-hong; Cao, Wen-jun; Zhang, Chao-ran
- Abstract
Purpose: To report atypical clinical features and diagnosis of stromal herpes simplex keratitis (HSK) and to evaluate the diagnostic efficiency of tear HSV-sIgA in atypical HSK. Study design: Prospective observational study. Methods: Records of keratitis' patients with tear herpes simplex virus (HSV)-sIgA test results acquired between May 2019 and November 2021 were evaluated retrospectively. Positive tear HSV-sIgA test was used to identify herpes simplex virus (HSV) infection. Patients with typical presentations and histories of HSV keratitis (HSK) were excluded. Results: Eleven eyes of 11 patients initially diagnosed as keratitis caused by other etiology were confirmed as having HSV infection by positive results of tear HSV-sIgA. Clinical features of atypical stromal HSK were variable. Antiviral treatment was effective in all patients. Conclusion: The appearance of an atypical stromal HSK represents a diagnostic challenge. Tear HSV-sIgA test could help provide a quick diagnosis.
- Subjects
HERPES simplex; KERATITIS; EYE infections; HERPES simplex virus
- Publication
Japanese Journal of Ophthalmology, 2023, Vol 67, Issue 1, p43
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-022-00963-8