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- Title
Anterior segment mechanisms of protection during herpes simplex virus 1 infection.
- Authors
Atherton, Sally S.; Cathcart, Heather M.
- Abstract
The article presents a study to identify cells and cytokines involved in early protection against the spread of herpes simplex virus (HSV) from the anterior to the central nervous system (CNS) to the optic nerve and into the retina. HSV is the leading cause of infectious corneal blindness in the U.S. and the major cause of corneal opacity worldwide. Mouse models with acute retinal necrosis (ARN) were used in the study. Photomicrographs showing the ciliary body of eye with HSV-1, uninfected control, and virus-infected mice are presented.
- Subjects
CYTOKINES; HERPES simplex virus; CENTRAL nervous system; OPTIC nerve; RETINA
- Publication
Japanese Journal of Ophthalmology, 2010, Vol 54, Issue 3, p182
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-010-0798-9