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- Title
Case Report: Clear Cell Odontogenic Carcinoma.
- Authors
Mariedina, Causa Trisna; Ismida, Fitri Dewi; Wahyuni, Sri
- Abstract
Introduction: Malignant odontogenic tumors account for 6% of the total number of odontogenic tumors. Clear cell odontogenic carcinoma (COdC) is an uncommon tumor originating from the odontogenic cells. Initially documented in 1985, but formally acknowledged as a cancerous growth in 2005. The majority of instances are observed in females between the ages of 40 and 59. The mandible is more prevalent in the maxilla. Case description: A 38-yearold man with complaint of painless swelling in the right cheek area persisting for the last 6 months. A panoramic radiograph and computed tomography (CT) scan of the head were conducted. Upon macroscopic inspection, two tissue samples from the mandible were received. The color was grayish white with an uneven surface and a rubbery substance. The tissue taken from the jaw showed an abundance of tumor cells that formed clusters within hyalinized stroma. The tumor cells exhibit a polygonal morphology, with enlarged nuclei that are round to oval in form. The nuclei are hyperchromatic, with some of the chromatin displaying a coarse texture. The nucleoli are prominently visible, and the cytoplasm appears clear. There is no evidence of lymphovascular and perineural invasion in this particular patient. Discussion: The patient was diagnosed as clear cell odontogenic carcinoma based on the findings from clinical, radiographic, and microscopic investigations. The tumor was determined to have no lymphovascular invasion or perineural invasion, and it was classified according to the International Classification of Diseases for Oncology (ICD-O) as 9341/3.
- Subjects
RENAL cell carcinoma; NOSOLOGY; ODONTOGENIC tumors; AMELOBLASTOMA; COMPUTED tomography; TUMOR classification
- Publication
Malaysian Journal of Medicine & Health Sciences, 2024, Vol 20, p100
- ISSN
1675-8544
- Publication type
Case Study