We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The semi-quantitative distribution of T4 and T6 surface antigens on human Langerhans cells.
- Authors
Schmitt, D.; Faure, M.; Dambuyant-Dezutter, C.; Thivolet, J.
- Abstract
We have used indirect immunogold electron microscopy to compare the respective density of cell membrane determinants revealed by OKT6 and OKT4 monoclonal antibodies on normal human Langerhans cells (LC): 12.9 ± 3.5 gold granules were noted per cell section on OKT4-positive LC whereas 236.8 ± 23.5 granules were counted per cell section on OKT6-reactive cells. These results confirm that human LC react with OKT4 antibody and they demonstrate a marked quantitative difference on LC surface between the antigenic determinants recognized by OKT6 and OKT4 antibodies.
- Subjects
IMMUNOGLOBULINS; CELLS; DENDRITIC cells; EPIDERMIS; CELL membranes; EPITOPES
- Publication
British Journal of Dermatology, 1984, Vol 111, Issue 6, p655
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/j.1365-2133.1984.tb14148.x