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- Title
Management of disorders of sex development, Jakarta cases.
- Authors
Giovanny, A.; Wahyudi, I.; Situmorang, G. R.; Rodjani, A.
- Abstract
Introduction: Disorders of sex development (DSD), defined as congenital condition associated with atypical development of chromosomal, gonadal, and phenotypic sex abnormalities, is a social burden for the neonatal period, yet there's still limited data on the incidence, diagnostic and management of DSD. Materials and Methods: Data were collected from medical records of patients with DSD managed by urologist, pediatric endocrinologist, and reproductive gynaecologist at CiptoMangunkusumo Hospital from January 2005 to July 2014. The 2006 International Intersex Consensus Conference Participant (IICCP) classification was used as classification. The profile and management of DSD were evaluated. Results: Out of 182 DSD cases, type 46 XX DSD had the highest incidence (46%) with majority of CAH, followed by 46 XY DSD (33%) with majority of AIS. Most cases were diagnosed at = 1 year of age (41%) and = 11 years (31%). As many as 83% of 46 XY DSD cases were raised as male, and 83% of 46 XX DSD cases were raised as female. Genitography had been used in 11 cases, urethroscopy and colposcopy used in 7 case, and diagnostic laparoscopy in 13 case. thirty persent of 46XY cases raised as a female having cross gender assignment, while 3/14 of 46 XX cases raised as male having cross gender assignment. Medical treatment was the most common treatment for Turner syndrome and CAH, while AIS was mostly treated with orchidopexy, and a total of 73 surgeries were done in all case. Conclusion: Most cases of DSD in CiptoMangunkusumo Hospital were CAH and AIS. Genitography, urethroscopy and colposcopy, and diagnostic laparoscopy have been used in the diagnosis of DSD. Forty percentof all DSD cases were treated with surgical treatment.
- Subjects
URETHROSCOPY; COLPOSCOPY; ENDOSCOPY; ORCHIOPEXY; EPIDEMIOLOGY
- Publication
BJU International, 2014, Vol 114, p5
- ISSN
1464-4096
- Publication type
Article