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- Title
Vitamins E and C in the Prevention of Prostate and Total Cancer in Men.
- Authors
Gaziano, J. Michael; Glynn, Robert J.; Christen, William G.; Kurth, Tobias; Belanger, Charlene; MacFadyen, Jean; Bubes, Vadim; Manson, JoAnn E.; Sesso, Howard D.; Buring, Julie E.
- Abstract
The article presents a randomized controlled trial which examined whether long term supplementation with vitamins E and C reduced the risk of prostate or total cancer in men. The Physician's Health Study II, which began in 1997 and ended in 2007, included 14,641 male physicians in the U.S. initially aged 50 years or older. Participants took 400 IU of vitamin E every other day and 500 mg of vitamin C daily. The main outcome was prostate and total cancer. Researchers found that neither vitamin E nor C supplementation reduced the risk of prostate or total cancer.
- Subjects
RANDOMIZED controlled trials; PROSTATE cancer prevention; THERAPEUTIC use of vitamin E; THERAPEUTIC use of vitamin C; MEN'S health; CANCER risk factors
- Publication
JAMA: Journal of the American Medical Association, 2009, Vol 301, Issue 1, p52
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.2008.862