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- Title
Missed Insulin Boluses for Snacks in Youth With Type 1 Diabetes.
- Authors
VanderWel, Brandon W.; Messer, Laurel H.; Horton, Lauren A.; McNair, Bryan; Cobry, Erin C.; McFann, Kim K.; Chase, H. Peter
- Abstract
OBJECTIVE -- To evaluate the effects of missed insulin boluses for snacks in youth with type 1 diabetes. RESEARCH DESIGN AND METHODS-- Three months of simultaneous continuous subcutaneous insulin infusion and continuous glucose monitoring data from nine subjects were retrospectively evaluated. Glucose excursions between 1330 and 1700 h were defined as relating to snacks with insulin or snacks with no insulin administered. Area under the curve > 180 mg/dl (AUC > 180), average Δ glucose, and rate of change were analyzed and compared within and between groups. RESULTS -- A total of 94 snacks without insulin and 101 snacks with insulin were analyzed. Snacks without insulin had significantly higher log (AUC >180 + 1) (1.26 vs. 0.44 mg/dl per event; P < 0.001), Δ glucose (114 vs. 52 mg/dl; P < 0.001), and average rate of change (1.3 vs. 1.1 mg/dl per minute; P < 0.001). CONCLUSIONS -- This study shows that afternoon snacks without insulin boluses are common and result in significantly higher glucose excursions than snacks with insulin administration.
- Subjects
INSULIN; SNACK foods; DIABETES in adolescence; BLOOD sugar; DIABETES; PEOPLE with diabetes
- Publication
Diabetes Care, 2010, Vol 33, Issue 3, p507
- ISSN
0149-5992
- Publication type
Article
- DOI
10.2337/dc09-1840