We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Risk factors associated to diabetes in Mexican population and phenotype of the individuals who will convert to diabetes.
- Authors
González-Villalpando, Clicerio; Dávila-Cervantes, Claudio Alberto; Zamora-Macorra, Mireya; Trejo-Valdivia, Belem; González-Villalpando, María Elena
- Abstract
Objective. To describe risk factors associated to the incidence of type 2 diabetes (T2D) in Mexican population and to define phenotypic (clinical, anthropometric, metabolic) characteristics present in the individual who will convert to diabetes, regardless of time of onset. Materials and methods. The Mexico City Diabetes Study began in 1990, with 2 282 participants, and had three subsequent phases: 1994, 1998, and 2008. A systematic evaluation with an oral glucose tolerance test was performed in each phase. For diagnosis of T2D, American Diabetes Association criteria were used. Results. The population at risk was 1 939 individuals. Subjects who were in the converter stage (initially non diabetic that eventually converted to T2D) had, at baseline, higher BMI (30 vs 27), systolic blood pressure (119 vs 116 mmHg), fasting glucose (90 vs 82mg/dl), triglycerides (239 vs I96mg/ dl), and cholesterol (192 vs l90mg/dl), compared with subjects who remained non converters (p<0.05). Conclusion. The phenotype described represents a potentially identifiable phase and a target for preventive intervention.
- Subjects
MEXICO City (Mexico); DISEASE incidence; TYPE 2 diabetes risk factors; MEXICANS; GLUCOSE tolerance tests; BLOOD sugar measurement; ANALYSIS of triglycerides; BLOOD pressure measurement; DISEASES
- Publication
Salud Pública de México, 2014, Vol 56, Issue 4, p317
- ISSN
0036-3634
- Publication type
Article